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How Blood-Brain Barrier Failure Drives CTE in Athletes

Mind & Behavior

Key takeaway

Repeated head impacts in athletes can cause a leaky blood-brain barrier, leading to toxic protein buildup and dementia-like symptoms. This finding points to new ways to diagnose and treat these brain injuries early on.

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Quick Explainer

New research has identified a leaky blood-brain barrier as the primary mechanism linking repetitive head injuries to long-term cognitive decline in retired athletes, leading to a buildup of toxic proteins associated with Alzheimer's and dementia.

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